The Refuge offers many activities for visitors. Bison, elk, deer, and prairie dogs can be seen along the wildlife drive at all times of the year. Interpretive displays at the visitor center describe the history and ecology of the area. Hiking trails lead to Fort Falls and, for the more adventurous, into the Niobrara River Wilderness Area. Canoeing or tubing through down the Niobrara National Scenic River is a popular activity on the Refuge.